STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
btkTyrosine-protein kinase. (635 aa)    
Predicted Functional Partners:
LOC113034959
B cell linker.
   
 0.932
LOC113022754
Tankyrase_bdg_C domain-containing protein.
    
 0.887
met
MET proto-oncogene, receptor tyrosine kinase.
    
0.823
LOC113022284
Macrophage stimulating 1 receptor a.
    
0.823
mst1r
Macrophage stimulating 1 receptor b.
    
0.823
pik3r5
Phosphoinositide-3-kinase, regulatory subunit 5.
   
 
  0.819
LOC113013036
Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.
    
  0.793
ENSACLP00000016464
Tyrosine-protein kinase.
   
0.788
syk
Tyrosine-protein kinase.
   
0.788
grb2
Growth factor receptor-bound protein 2b.
   
0.755
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.