STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000003331SMC_N domain-containing protein. (1078 aa)    
Predicted Functional Partners:
nsmce2
NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase.
    
 0.999
nsmce1
NSE1 homolog, SMC5-SMC6 complex component.
    
 0.999
nsmce4a
Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
   
 0.996
ENSACLP00000004637
Structural maintenance of chromosomes 6.
   
0.994
LOC113013820
Necdin-like 2.
   
 0.994
smc6
Si:dkey-119f1.1.
   
0.994
ENSACLP00000009352
SMC5-SMC6 complex localization factor 1.
  
 
 0.947
sumo1
Small ubiquitin-related modifier.
    
 0.943
fancm
Uncharacterized protein.
   
 
 0.943
ENSACLP00000013582
Uncharacterized protein.
   
 0.939
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.