Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000003336Uncharacterized protein. (362 aa)    
Predicted Functional Partners:
ctnnb1
Catenin (cadherin-associated protein), beta 1.
   
 0.916
ENSACLP00000003395
Chromo domain-containing protein.
 
      0.876
LOC113014539
Uncharacterized protein.
   
 0.855
leo1
LEO1 homolog, Paf1/RNA polymerase II complex component.
   
 
 0.810
ENSACLP00000020446
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
    
 
 0.798
ENSACLP00000040644
RTF1 homolog, Paf1/RNA polymerase II complex component.
   
 
 0.798
supt16h
SPT16 homolog, facilitates chromatin remodeling subunit.
    
 
 0.797
ENSACLP00000009258
Chromo domain-containing protein.
 
      0.755
ash2l
Ash2 like, histone lysine methyltransferase complex subunit.
    
 
 0.739
rbbp5
Retinoblastoma binding protein 5.
    
 
 0.725
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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