STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000003336Uncharacterized protein. (362 aa)    
Predicted Functional Partners:
ENSACLP00000003395
Chromo domain-containing protein.
 
      0.876
ENSACLP00000020446
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
    
 
 0.808
actr5
Actin related protein 5; Belongs to the actin family.
    
 0.800
ruvbl1
RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.
    
 0.798
polr2f
Polymerase (RNA) II (DNA directed) polypeptide F.
   
 0.789
ENSACLP00000034796
Translocase of outer mitochondrial membrane 20.
   
 0.789
polr2c
Polymerase (RNA) II (DNA directed) polypeptide C.
   
 0.785
fancm
Uncharacterized protein.
   
 0.785
ENSACLP00000008692
AT rich interactive domain 4A (RBP1-like).
    
 0.784
ctnnb1
Catenin (cadherin-associated protein), beta 1.
   
 0.775
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.