STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GET1Guided entry of tail-anchored proteins factor 1. (170 aa)    
Predicted Functional Partners:
get3
ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]
    
 0.997
camlg
Calcium modulating ligand.
    
 0.985
ENSACLP00000010870
Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.
    
 0.808
get4
Guided entry of tail-anchored proteins factor 4.
    
 0.740
sgta
Small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha.
    
 0.683
ENSACLP00000039857
Small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta.
    
 0.683
tmem208
Transmembrane protein 208.
    
 
 0.639
emc6
ER membrane protein complex subunit 6.
    
 
 0.620
ttc33
Tetratricopeptide repeat domain 33.
    
 0.609
cog6
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.
    
   0.589
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.