Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC113012817Si:dkey-6n6.2. (300 aa)    
Predicted Functional Partners:
ak9
Adenylate kinase 9.
   
  0.869
acp1
LMWPc domain-containing protein.
    
  0.850
LOC113035320
Multiple inositol-polyphosphate phosphatase 1a; Belongs to the histidine acid phosphatase family.
    
 0.807
ENSACLP00000022773
Multiple inositol-polyphosphate phosphatase 1a; Belongs to the histidine acid phosphatase family.
    
 0.807
LOC113027916
Uncharacterized protein; Belongs to the histidine acid phosphatase family.
    
 0.807
asmtl
Acetylserotonin O-methyltransferase-like.
   
 
  0.796
MTAP
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
   
   0.766
nudt12
Nudix (nucleoside diphosphate linked moiety X)-type motif 12.
   
 0.759
txnl4a
Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family.
    
   0.750
alpl
Alkaline phosphatase.
    
 0.733
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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