Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pyglAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (853 aa)    
Predicted Functional Partners:
agl
Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase b.
  
 0.994
gbe1
Glucan (1,4-alpha-), branching enzyme 1b.
  
 0.987
pgm1
Phosphoglucomutase 1; Belongs to the phosphohexose mutase family.
  
 
 0.977
ENSACLP00000019962
Uncharacterized protein; Belongs to the phosphohexose mutase family.
  
 
 0.976
LOC113033888
Phosphoglucomutase 5; Belongs to the phosphohexose mutase family.
  
 
 0.957
calm1
Calmodulin 2a (phosphorylase kinase, delta); Belongs to the calmodulin family.
    
 0.956
calm1-2
Calmodulin 3a (phosphorylase kinase, delta); Belongs to the calmodulin family.
    
 0.956
calm1-3
Calmodulin.
    
 0.956
ENSACLP00000037109
Uncharacterized protein; Belongs to the calmodulin family.
    
 0.956
gys1
Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.
  
 0.954
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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