STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000003429RWD domain-containing protein. (141 aa)    
Predicted Functional Partners:
eif2s1
Eukaryotic translation initiation factor 2, subunit 1 alpha b.
   
 0.993
ENSACLP00000001083
GCN1 activator of EIF2AK4.
   
 
 0.944
eif2s3
Eukaryotic translation initiation factor 2, subunit 3 gamma.
   
 0.924
ENSACLP00000018362
Serine/threonine-protein kinase TOR.
   
 0.921
eif2ak3
Eukaryotic translation initiation factor 2-alpha kinase 3.
   
 
 0.917
hars1
Histidyl-tRNA synthetase.
     
 0.916
eif2b1
Eukaryotic translation initiation factor 2B, subunit 1 alpha; Belongs to the eIF-2B alpha/beta/delta subunits family.
   
 
 0.910
eif2ak1
Eukaryotic translation initiation factor 2-alpha kinase 1.
   
 0.904
eif2a
Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.
   
 
 0.902
rptor
Regulatory associated protein of MTOR, complex 1.
    
 0.896
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.