Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000003449Catenin (cadherin-associated protein), alpha 1. (923 aa)    
Predicted Functional Partners:
ctnnb1
Catenin (cadherin-associated protein), beta 1.
   
 0.989
LOC113014539
Uncharacterized protein.
   
 0.981
ENSACLP00000001671
Afadin, adherens junction formation factor a.
   
 0.973
ENSACLP00000003584
Uncharacterized protein.
   
 0.973
ENSACLP00000009083
Vinculin a.
   
 0.968
vcl
Vinculin b.
   
 0.968
cdh5
Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.
    
  0.956
LOC113021483
Uncharacterized protein.
   
 0.954
LOC113023765
Junction plakoglobin a.
   
 0.954
LOC113035138
Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.
    
 0.950
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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