Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sgtaSmall glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha. (337 aa)    
Predicted Functional Partners:
LOC113033208
Ubiquitin-like domain-containing protein.
    
 0.972
get4
Guided entry of tail-anchored proteins factor 4.
   
 0.967
get3
ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]
   
 0.965
LOC113031594
BCL2 associated athanogene 6.
   
 0.952
LOC113014194
BCL2 associated athanogene 6, like.
   
 0.951
ENSACLP00000010870
Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.
    
 0.925
psmd14
Proteasome 26S subunit, non-ATPase 14.
   
  0.855
CLPB
ClpB homolog, mitochondrial AAA ATPase chaperonin.
  
 
 0.850
hspa4l
Heat shock protein 4 like.
  
 0.835
gosr2
Golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
   
   0.825
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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