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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
arhgef11Rho guanine nucleotide exchange factor (GEF) 11. (1449 aa)    
Predicted Functional Partners:
gna12
G protein subunit alpha 12.
    
 0.939
LOC113021491
Guanine nucleotide binding protein (G protein), alpha 13b.
    
 0.939
ENSACLP00000015907
Guanine nucleotide binding protein (G protein), alpha 13b.
    
 0.939
LOC113028194
Uncharacterized protein.
    
 0.939
ENSACLP00000012848
Uncharacterized protein.
   
 0.928
LOC113012818
Uncharacterized protein.
   
 0.914
LOC113013171
Uncharacterized protein.
   
 0.914
LOC113022452
Ras homolog gene family, member Ab.
   
 0.914
LOC113022007
Ras homolog family member Cb.
   
 0.914
mras
Muscle RAS oncogene homolog.
    
  0.852
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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