Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
frmd6FERM domain containing 6. (611 aa)    
Predicted Functional Partners:
yap1
Yes-associated protein 1.
   
 0.964
stk3
Serine/threonine kinase 3 (STE20 homolog, yeast).
    
 0.957
LOC113021863
Uncharacterized protein.
    
 0.957
LOC113030350
Neurofibromin 2b (merlin).
    
 0.906
nf2
Neurofibromin 2a (merlin).
    
 0.906
LOC113036715
F-box and WD repeat domain containing 11b.
    
 
 0.863
fat2
FAT atypical cadherin 2.
    
 0.862
fat1
FAT atypical cadherin 1a.
    
 0.862
lats1
Large tumor suppressor kinase 1.
    
 
 0.860
LOC113013952
Uncharacterized protein.
    
   0.840
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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