Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ENSACLP00000003575TYR_PHOSPHATASE_2 domain-containing protein. (158 aa)    
Predicted Functional Partners:
exosc8
Exosome component 8.
   
   0.894
espl1
Extra spindle pole bodies like 1, separase.
   
 0.857
cdc6
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
 
 0.814
LOC113013195
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
   
 0.766
ENSACLP00000004683
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
   
 0.766
LOC113018391
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
   
 0.766
ENSACLP00000027728
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
    
   0.731
nrde2
NRDE-2, necessary for RNA interference, domain containing.
    
 
 0.725
cdc27
Cell division cycle 27.
  
 0.713
ENSACLP00000030550
Growth arrest-specific 7a.
    
 0.701
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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