Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ENSACLP00000003610SWIM-type zinc finger 7 associated protein 1. (191 aa)    
Predicted Functional Partners:
spidr
Uncharacterized protein.
    
 
 0.995
zswim7
Zinc finger, SWIM-type containing 7.
    
 0.991
rad51
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
    
 
 0.866
rad51d
RAD51 paralog D.
    
 
 0.834
LOC113019998
Phospholipase A(2).
    
   0.763
xrcc3
DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.
    
 
 0.758
ENSACLP00000033842
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
      
 0.725
trip13
Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family.
    
 
 0.717
pds5b
PDS5 cohesin associated factor B.
    
 
 0.709
pds5a
PDS5 cohesin associated factor A.
    
 
 0.709
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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