Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SPTBN1Spectrin beta chain; Belongs to the spectrin family. (2374 aa)    
Predicted Functional Partners:
sptan1
Spectrin alpha, non-erythrocytic 1.
   
 0.964
LOC113030014
Spectrin beta chain; Belongs to the spectrin family.
  
  
 
0.905
ENSACLP00000026550
Spectrin beta chain; Belongs to the spectrin family.
  
  
 
0.884
LOC113030643
PH domain-containing protein.
     
  0.649
LOC113030687
Glutamate receptor, metabotropic 5a.
     
  0.590
LOC113011728
Glutamate receptor, metabotropic 1b.
     
  0.590
grm1
Glutamate receptor, metabotropic 1a.
     
  0.590
grm5
Glutamate receptor, metabotropic 5b.
     
  0.590
copb1
Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
    
 0.587
LOC113033420
Adducin 2 (beta).
    
 
 0.586
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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