RAPGEF5 protein (Astatotilapia calliptera) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

RAPGEF5

Uncharacterized protein. (596 aa)

Predicted Functional Partners:

ENSACLP00000008539

0.949

RIMS2

0.949

mras

0.925

LOC113008802

0.910

LOC113021951

0.910

LOC113021506

0.855

rras2

0.855

hras

0.753

LOC113020994

0.753

CSDE1

0.753

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSDE1	LOC113008802	ENSACLP00000019557	ENSACLP00000016790	Cold shock domain containing E1, RNA-binding.	Uncharacterized protein.	0.526
CSDE1	LOC113021506	ENSACLP00000019557	ENSACLP00000016488	Cold shock domain containing E1, RNA-binding.	RAS related.	0.781
CSDE1	LOC113021951	ENSACLP00000019557	ENSACLP00000029399	Cold shock domain containing E1, RNA-binding.	Uncharacterized protein.	0.526
CSDE1	RAPGEF5	ENSACLP00000019557	ENSACLP00000003631	Cold shock domain containing E1, RNA-binding.	Uncharacterized protein.	0.753
CSDE1	mras	ENSACLP00000019557	ENSACLP00000011401	Cold shock domain containing E1, RNA-binding.	Muscle RAS oncogene homolog.	0.831
CSDE1	rras2	ENSACLP00000019557	ENSACLP00000040133	Cold shock domain containing E1, RNA-binding.	RAS related 2.	0.781
ENSACLP00000008539	RAPGEF5	ENSACLP00000008539	ENSACLP00000003631	Uncharacterized protein.	Uncharacterized protein.	0.949
ENSACLP00000008539	RIMS2	ENSACLP00000008539	ENSACLP00000037307	Uncharacterized protein.	Regulating synaptic membrane exocytosis 2.	0.707
LOC113008802	CSDE1	ENSACLP00000016790	ENSACLP00000019557	Uncharacterized protein.	Cold shock domain containing E1, RNA-binding.	0.526
LOC113008802	LOC113020994	ENSACLP00000016790	ENSACLP00000010706	Uncharacterized protein.	Zgc:55558.	0.508
LOC113008802	RAPGEF5	ENSACLP00000016790	ENSACLP00000003631	Uncharacterized protein.	Uncharacterized protein.	0.910
LOC113008802	hras	ENSACLP00000016790	ENSACLP00000001697	Uncharacterized protein.	HRas proto-oncogene, GTPase a.	0.508
LOC113020994	LOC113008802	ENSACLP00000010706	ENSACLP00000016790	Zgc:55558.	Uncharacterized protein.	0.508
LOC113020994	LOC113021506	ENSACLP00000010706	ENSACLP00000016488	Zgc:55558.	RAS related.	0.781
LOC113020994	LOC113021951	ENSACLP00000010706	ENSACLP00000029399	Zgc:55558.	Uncharacterized protein.	0.508
LOC113020994	RAPGEF5	ENSACLP00000010706	ENSACLP00000003631	Zgc:55558.	Uncharacterized protein.	0.753
LOC113020994	hras	ENSACLP00000010706	ENSACLP00000001697	Zgc:55558.	HRas proto-oncogene, GTPase a.	0.857
LOC113020994	mras	ENSACLP00000010706	ENSACLP00000011401	Zgc:55558.	Muscle RAS oncogene homolog.	0.831
LOC113020994	rras2	ENSACLP00000010706	ENSACLP00000040133	Zgc:55558.	RAS related 2.	0.781
LOC113021506	CSDE1	ENSACLP00000016488	ENSACLP00000019557	RAS related.	Cold shock domain containing E1, RNA-binding.	0.781