| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ASS1 | ENSACLP00000022352 | ENSACLP00000017252 | ENSACLP00000022352 | Argininosuccinate synthase 1. | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.942 |
| ASS1 | LOC113007106 | ENSACLP00000017252 | ENSACLP00000003644 | Argininosuccinate synthase 1. | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | 0.984 |
| ASS1 | LOC113030808 | ENSACLP00000017252 | ENSACLP00000013856 | Argininosuccinate synthase 1. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.920 |
| ASS1 | LOC113031405 | ENSACLP00000017252 | ENSACLP00000011040 | Argininosuccinate synthase 1. | Cytochrome b5 reductase 4. | 0.674 |
| ASS1 | adss1 | ENSACLP00000017252 | ENSACLP00000004638 | Argininosuccinate synthase 1. | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.920 |
| ASS1 | gart | ENSACLP00000017252 | ENSACLP00000036327 | Argininosuccinate synthase 1. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.636 |
| ASS1 | otc | ENSACLP00000017252 | ENSACLP00000004466 | Argininosuccinate synthase 1. | Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.996 |
| ASS1 | umps | ENSACLP00000017252 | ENSACLP00000012513 | Argininosuccinate synthase 1. | Uridine monophosphate synthetase. | 0.588 |
| ENSACLP00000002716 | ENSACLP00000022352 | ENSACLP00000002716 | ENSACLP00000022352 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.665 |
| ENSACLP00000002716 | LOC113007106 | ENSACLP00000002716 | ENSACLP00000003644 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | 0.953 |
| ENSACLP00000002716 | LOC113030808 | ENSACLP00000002716 | ENSACLP00000013856 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.815 |
| ENSACLP00000002716 | LOC113031405 | ENSACLP00000002716 | ENSACLP00000011040 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Cytochrome b5 reductase 4. | 0.993 |
| ENSACLP00000002716 | adss1 | ENSACLP00000002716 | ENSACLP00000004638 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.815 |
| ENSACLP00000002716 | dhodh | ENSACLP00000002716 | ENSACLP00000037514 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.533 |
| ENSACLP00000002716 | gart | ENSACLP00000002716 | ENSACLP00000036327 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.787 |
| ENSACLP00000002716 | umps | ENSACLP00000002716 | ENSACLP00000012513 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Uridine monophosphate synthetase. | 0.991 |
| ENSACLP00000022352 | ASS1 | ENSACLP00000022352 | ENSACLP00000017252 | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | Argininosuccinate synthase 1. | 0.942 |
| ENSACLP00000022352 | ENSACLP00000002716 | ENSACLP00000022352 | ENSACLP00000002716 | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | 0.665 |
| ENSACLP00000022352 | LOC113007106 | ENSACLP00000022352 | ENSACLP00000003644 | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | 0.965 |
| ENSACLP00000022352 | LOC113030808 | ENSACLP00000022352 | ENSACLP00000013856 | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.946 |