Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dctn4Dynactin 4. (469 aa)    
Predicted Functional Partners:
dctn5
Dynactin 5.
    
 0.999
dctn2
Dynactin 2 (p50).
   
 0.999
LOC113012252
Uncharacterized protein.
    
 0.998
DCTN6
Dynactin subunit 6.
    
 0.998
actr10
Actin related protein 10; Belongs to the actin family.
   
 0.998
dctn3
Dynactin 3 (p22).
    
 0.997
LOC113026320
Actin related protein 1, centractin.
   
 0.995
LOC113018559
CAP-Gly domain-containing protein.
    
 0.993
ENSACLP00000040036
Dynactin 1b.
    
 0.993
capzb
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
    
 0.980
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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