Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000003678TPX2 microtubule nucleation factor. (621 aa)    
Predicted Functional Partners:
LOC113008948
Aurora kinase B; Belongs to the protein kinase superfamily.
   
 0.989
aurka
Aurora kinase A; Belongs to the protein kinase superfamily.
   
 0.989
dlgap5
Discs, large (Drosophila) homolog-associated protein 5.
   
  
 0.976
ENSACLP00000002644
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
 0.969
ube2c
Ubiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family.
   
 
 0.967
LOC113028579
Baculoviral IAP repeat containing 5a.
   
 0.964
ENSACLP00000013937
Centromere protein F.
   
 
 0.952
melk
Non-specific serine/threonine protein kinase.
   
 0.952
ENSACLP00000013582
Uncharacterized protein.
   
 
 0.949
bub1b
BUB1 mitotic checkpoint serine/threonine kinase Bb.
   
  
 0.936
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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