Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
ENSACLP00000003704Striatin, calmodulin binding protein. (779 aa)    
Predicted Functional Partners:
map2k7
Mitogen-activated protein kinase kinase 7.
   
  0.920
strip1
Striatin interacting protein 1.
    
 
 0.911
ENSACLP00000004817
Striatin interacting protein 2.
    
 
 0.907
LOC113007291-2
MOB family member 4, phocein.
   
 
 0.901
slmap
Sarcolemma associated protein a.
   
 
 0.874
LOC113036096
Protein phosphatase 2, regulatory subunit A, beta b.
    
 
 0.869
ENSACLP00000013574
CTTNBP2 N-terminal like b.
   
 
 0.861
LOC113021954
CTTNBP2 N-terminal like a.
   
 
 0.844
RNF8
E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]
    
 
 0.842
suox
Sulfite oxidase.
    
   0.836
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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