def6 protein (Astatotilapia calliptera) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

def6

DEF6 guanine nucleotide exchange factor a. (617 aa)

Predicted Functional Partners:

UNC79

0.861

LOC113022989

0.676

LOC113007418

0.657

ak9

0.616

ENSACLP00000037094

0.597

rbbp5

0.569

ENSACLP00000008539

0.569

LOC113015068

0.569

ENSACLP00000023060

0.569

LOC113015067

0.569

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSACLP00000008539	UNC79	ENSACLP00000008539	ENSACLP00000032637	Uncharacterized protein.	Unc-79 homolog, NALCN channel complex subunit.	0.752
ENSACLP00000008539	def6	ENSACLP00000008539	ENSACLP00000003706	Uncharacterized protein.	DEF6 guanine nucleotide exchange factor a.	0.569
ENSACLP00000023060	ENSACLP00000037094	ENSACLP00000023060	ENSACLP00000037094	Cell division cycle 42, like.	Im:7152348.	0.825
ENSACLP00000023060	LOC113007418	ENSACLP00000023060	ENSACLP00000030257	Cell division cycle 42, like.	RAN binding protein 2.	0.415
ENSACLP00000023060	LOC113022989	ENSACLP00000023060	ENSACLP00000036531	Cell division cycle 42, like.	Cell division cycle 42.	0.723
ENSACLP00000023060	def6	ENSACLP00000023060	ENSACLP00000003706	Cell division cycle 42, like.	DEF6 guanine nucleotide exchange factor a.	0.569
ENSACLP00000037094	ENSACLP00000023060	ENSACLP00000037094	ENSACLP00000023060	Im:7152348.	Cell division cycle 42, like.	0.825
ENSACLP00000037094	LOC113007418	ENSACLP00000037094	ENSACLP00000030257	Im:7152348.	RAN binding protein 2.	0.456
ENSACLP00000037094	LOC113015067	ENSACLP00000037094	ENSACLP00000023081	Im:7152348.	Cell division cycle 42, like.	0.825
ENSACLP00000037094	LOC113015068	ENSACLP00000037094	ENSACLP00000023023	Im:7152348.	Cell division cycle 42, like.	0.825
ENSACLP00000037094	LOC113022989	ENSACLP00000037094	ENSACLP00000036531	Im:7152348.	Cell division cycle 42.	0.825
ENSACLP00000037094	def6	ENSACLP00000037094	ENSACLP00000003706	Im:7152348.	DEF6 guanine nucleotide exchange factor a.	0.597
LOC113007418	ENSACLP00000023060	ENSACLP00000030257	ENSACLP00000023060	RAN binding protein 2.	Cell division cycle 42, like.	0.415
LOC113007418	ENSACLP00000037094	ENSACLP00000030257	ENSACLP00000037094	RAN binding protein 2.	Im:7152348.	0.456
LOC113007418	LOC113015067	ENSACLP00000030257	ENSACLP00000023081	RAN binding protein 2.	Cell division cycle 42, like.	0.415
LOC113007418	LOC113015068	ENSACLP00000030257	ENSACLP00000023023	RAN binding protein 2.	Cell division cycle 42, like.	0.415
LOC113007418	LOC113022989	ENSACLP00000030257	ENSACLP00000036531	RAN binding protein 2.	Cell division cycle 42.	0.415
LOC113007418	def6	ENSACLP00000030257	ENSACLP00000003706	RAN binding protein 2.	DEF6 guanine nucleotide exchange factor a.	0.657
LOC113015067	ENSACLP00000037094	ENSACLP00000023081	ENSACLP00000037094	Cell division cycle 42, like.	Im:7152348.	0.825
LOC113015067	LOC113007418	ENSACLP00000023081	ENSACLP00000030257	Cell division cycle 42, like.	RAN binding protein 2.	0.415