STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KPNA2Importin subunit alpha; Belongs to the importin alpha family. (524 aa)    
Predicted Functional Partners:
ENSACLP00000034336
CSE1 chromosome segregation 1-like (yeast).
   
 0.946
kpnb1
Karyopherin (importin) beta 1.
   
 0.945
nup50
Nucleoporin 50.
   
 
 0.837
nup153
Nucleoporin 153.
   
 
 0.834
NCBP1
Nuclear cap binding protein subunit 1.
   
 
 0.825
kpna3
Importin subunit alpha; Belongs to the importin alpha family.
    
  0.820
kpna4
Importin subunit alpha; Belongs to the importin alpha family.
    
  0.820
ncbp2
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]
    
 
 0.807
dlgap5
Discs, large (Drosophila) homolog-associated protein 5.
   
  
 0.796
ccnb1
Cyclin B1; Belongs to the cyclin family.
   
 0.791
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.