Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000003770TNFAIP3 interacting protein 1. (652 aa)    
Predicted Functional Partners:
tnfaip3
Tumor necrosis factor, alpha-induced protein 3.
   
 0.998
optn
Optineurin.
    
 0.988
LOC113031642
Tumor necrosis factor b (TNF superfamily, member 2).
    
 
 0.979
LOC113032516
Tumor necrosis factor receptor superfamily, member 1a.
    
 
 0.976
ENSACLP00000005014
Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100).
   
 
 0.905
nfkb1
Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1.
   
 
 0.905
tax1bp1
Tax1 (human T-cell leukemia virus type I) binding protein 1b.
    
 
 0.901
LOC113013036
Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.
    
 0.882
rb1cc1
RB1-inducible coiled-coil 1.
    
   0.878
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
    
 
 0.856
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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