Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000003788SH3 and multiple ankyrin repeat domains 2a. (1506 aa)    
Predicted Functional Partners:
dhrs7b
Dehydrogenase/reductase (SDR family) member 7B; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
   0.974
ENSACLP00000003818
Uncharacterized protein.
 
 
 0.945
dlgap3
Discs, large (Drosophila) homolog-associated protein 3.
   
 0.930
LOC113022727
Discs, large (Drosophila) homolog-associated protein 4b.
   
 0.915
ENSACLP00000018695
PDZ domain-containing protein.
   
 0.891
shank1
SH3 and multiple ankyrin repeat domains 1.
   
 0.891
shank3
SH3 and multiple ankyrin repeat domains 3a.
   
 0.891
ENSACLP00000007745
Discs, large (Drosophila) homolog-associated protein 1a.
   
 0.883
ENSACLP00000027090
Discs, large (Drosophila) homolog-associated protein 2a.
   
 0.883
ENSACLP00000037529
Discs, large (Drosophila) homolog-associated protein 2b.
   
 0.883
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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