Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (692 aa)    
Predicted Functional Partners:
ENSACLP00000017922
Cys_knot domain-containing protein.
   
 0.973
TSHB
Thyroid stimulating hormone subunit beta.
    
 0.929
ENSACLP00000033161
Thyroid stimulating hormone subunit beta a.
    
 0.929
cga
Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family.
    
 0.898
ENSACLP00000031592
Glycoprotein hormone subunit alpha 2.
    
 0.889
ENSACLP00000020432
Guanine nucleotide binding protein (G protein), beta polypeptide 2.
    
  0.880
gnb4
Guanine nucleotide binding protein (G protein), beta polypeptide 4b.
    
  0.880
ENSACLP00000000722
Cys_knot domain-containing protein.
   
 0.879
gphb5
Glycoprotein hormone subunit beta 5.
     
 0.879
ENSACLP00000031551
Si:dkey-23i12.9.
     
 0.879
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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