Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACLP00000003812Si:ch211-215j19.12; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (177 aa)    
Predicted Functional Partners:
ENSACLP00000002063
Uncharacterized protein.
    
 0.968
nppc
Natriuretic peptide C.
    
 0.955
ENSACLP00000002077
Natriuretic peptide B.
    
 0.948
ENSACLP00000020243
Protein kinase domain-containing protein.
 
   
  0.937
ENSACLP00000000318
Phosphodiesterase.
    
 0.844
LOC113022754
Tankyrase_bdg_C domain-containing protein.
     
  0.830
LOC113013643
Natriuretic peptide A-like.
     
 0.827
ENSACLP00000031592
Glycoprotein hormone subunit alpha 2.
    
  0.820
vip
Vasoactive intestinal peptide.
   
 
 0.820
pde6d
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide [...]
    
 0.818
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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