Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
apc2APC regulator of WNT signaling pathway 2. (2611 aa)    
Predicted Functional Partners:
ctnnb1
Catenin (cadherin-associated protein), beta 1.
   
 0.990
AXIN2
Axin 2.
   
 0.984
LOC113020813
Axin 2 (conductin, axil).
   
 0.984
ENSACLP00000007241
Uncharacterized protein.
   
 0.981
axin1
Axin 1.
   
 0.981
LOC113014539
Uncharacterized protein.
   
 0.978
gsk3b
Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily.
    
 0.977
LOC113014387
Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily.
    
 0.953
LOC113032794
Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily.
    
 0.953
LOC113021483
Uncharacterized protein.
   
 0.951
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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