Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gclmGlutamate-cysteine ligase, modifier subunit. (277 aa)    
Predicted Functional Partners:
gclc
Glutamate-cysteine ligase, catalytic subunit.
   
 0.999
gss
Glutathione synthetase.
   
 0.917
ENSACLP00000015133
GSH_synthase domain-containing protein.
   
 0.917
ENSACLP00000018940
GSH_synthase domain-containing protein.
   
 0.917
ENSACLP00000019317
GSH_synthase domain-containing protein.
   
 0.917
ENSACLP00000021684
GSH_synthase domain-containing protein.
   
 0.917
hykk
Hydroxylysine kinase, tandem duplicate 1.
  
 
 0.913
kyat3
Kynurenine aminotransferase 3.
  
 
 0.908
kyat1
Kynurenine aminotransferase 1.
  
 
 0.908
cth
Cystathionase (cystathionine gamma-lyase), like.
    
 0.907
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.