close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000003943Cholesterol 25-hydroxylase like 3; Belongs to the sterol desaturase family. (270 aa)    
Predicted Functional Partners:
LOC113010228
Cytochrome P450, family 7, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family.
   
 0.954
LOC113011007
Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.
   
 0.954
LOC113027168
Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.
   
 0.940
ENSACLP00000032963
Sterol-C5-desaturase; Belongs to the sterol desaturase family.
   
 0.940
dhcr7
7-dehydrocholesterol reductase.
   
 0.935
tm7sf2
Transmembrane 7 superfamily member 2.
   
 0.921
lbr
Lamin B receptor.
   
 0.921
LOC113031766
Squalene epoxidase a.
   
 0.919
ENSACLP00000038598
SE domain-containing protein.
   
 0.919
LOC113016200
Hydroxysteroid (17-beta) dehydrogenase 7.
   
 0.912
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.