Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
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Co-expression
Experiments
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[Homology]
Score
ENSACLP00000003943Cholesterol 25-hydroxylase like 3; Belongs to the sterol desaturase family. (270 aa)    
Predicted Functional Partners:
LOC113010228
Cytochrome P450, family 7, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family.
   
 0.947
LOC113011007
Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.
   
 0.947
dhcr7
7-dehydrocholesterol reductase.
   
 0.927
LOC113027168
Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.
   
 0.921
ENSACLP00000032963
Sterol-C5-desaturase; Belongs to the sterol desaturase family.
   
 0.921
dhcr24
24-dehydrocholesterol reductase.
  
 
 0.914
LOC113021918
O-acyltransferase.
   
 0.896
soat1
O-acyltransferase.
   
 0.896
sigmar1
Sigma non-opioid intracellular receptor 1.
   
 0.884
LOC113027912
Lipase; Belongs to the AB hydrolase superfamily. Lipase family.
   
 
 0.879
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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