STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC113010303Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1122 aa)    
Predicted Functional Partners:
pln
Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN.
    
 0.724
gak
Cyclin G associated kinase.
   
 
 0.699
ENSACLP00000007517
Uncharacterized protein.
   
 0.610
atp7a
ATPase copper transporting alpha.
   
0.610
ENSACLP00000016868
ATPase copper transporting beta.
   
0.610
nme9
NME/NM23 family member 8; Belongs to the NDK family.
   
 0.604
ENSACLP00000002940
DnaJ (Hsp40) homolog, subfamily C, member 6.
   
 
 0.581
atp5po
ATP synthase peripheral stalk subunit OSCP.
   
 0.562
LOC113037120
Cell cycle control protein; Belongs to the CDC50/LEM3 family.
    
 0.550
LOC113012734
Cell cycle control protein; Belongs to the CDC50/LEM3 family.
    
 0.550
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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