STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMURF2E3 ubiquitin-protein ligase. (776 aa)    
Predicted Functional Partners:
smad7
Mothers against decapentaplegic homolog.
    
 0.968
smad6
Mothers against decapentaplegic homolog.
    
 0.964
LOC113019522
Mothers against decapentaplegic homolog.
    
 0.964
RPS27A
Ribosomal protein S27a.
    
 0.935
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
 0.930
LOC113028987
Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    
 0.908
PTCH1
Patched 1.
    
 0.899
ptch2
Patched 2.
    
 0.891
TGFBR2
Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    
 0.890
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.889
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.