Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ENSACLP00000004042Limb and CNS expressed 1. (323 aa)    
Predicted Functional Partners:
fat2
FAT atypical cadherin 2.
   
 0.836
fat1
FAT atypical cadherin 1a.
   
 0.836
ENSACLP00000000428
FAT atypical cadherin 3b.
   
 0.774
ENSACLP00000034538
FAT atypical cadherin 3a.
   
 0.774
c22h1orf109
C19h1orf109 homolog (H. sapiens).
   
    0.764
cwc25
CWC25 spliceosome associated protein homolog.
   
    0.764
rubcnl
Rubicon like autophagy enhancer.
   
    0.764
mocs3
Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...]
   
    0.757
LOC113012501
Src homology 2 domain containing transforming protein D, a.
   
    0.750
c18h5orf22
Zgc:56556.
   
 0.737
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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