Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ccniCyclin I; Belongs to the cyclin family. (418 aa)    
Predicted Functional Partners:
cdc6
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
 0.883
cdc27
Cell division cycle 27.
    
 0.845
cdk5
Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.
    
 
 0.832
skp1
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
   
 0.822
ENSACLP00000027823
Anaphase promoting complex subunit 2; Belongs to the cullin family.
    
 0.808
LOC113027124
Wee1-like protein kinase.
   
 0.769
pkmyt1
Protein kinase, membrane associated tyrosine/threonine 1.
   
 0.769
wee1
Wee1-like protein kinase.
   
 0.769
FZR1
Fizzy/cell division cycle 20 related 1a.
   
 0.747
LOC113009944
Fizzy/cell division cycle 20 related 1b.
   
 0.747
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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