Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ENSACLP00000004060Tyrosine hydroxylase. (481 aa)    
Predicted Functional Partners:
PCBD2
Pterin-4 alpha-carbinolamine dehydratase 2.
  
 0.966
pcbd1
Pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha.
  
 0.966
LOC113025649
Uncharacterized protein; Belongs to the synuclein family.
    
 0.960
ddc
Dopa decarboxylase.
   
 0.942
ENSACLP00000028085
Histidine decarboxylase.
   
 0.942
got2
Aspartate aminotransferase.
  
 
 0.926
TYR
Tyrosinase.
     
 0.922
qdpr
Quinoid dihydropteridine reductase a.
   
 0.921
LOC113035691
Amine oxidase.
     
 0.921
tat
Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.
   
 
 0.915
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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