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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pms1PMS1 homolog 1, mismatch repair system component. (897 aa)    
Predicted Functional Partners:
ENSACLP00000031218
MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).
    
0.996
ENSACLP00000003108
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
 
 0.992
msh6
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
 
 0.990
ENSACLP00000033842
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
 
 0.981
msh3
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
 
 0.974
ENSACLP00000013446
Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.
   
 0.971
ENSACLP00000007406
Exonuclease 1.
   
 0.961
ENSACLP00000011862
MutS homolog 5.
 
 0.960
ENSACLP00000011868
Uncharacterized protein.
  
 0.950
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.917
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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