STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ormdl1ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)    
Predicted Functional Partners:
sptssa
Serine palmitoyltransferase, small subunit A.
    
 
 0.941
sptlc1
Serine palmitoyltransferase, long chain base subunit 1.
    
 
 0.892
ddost
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...]
    
   0.725
pigo
Phosphatidylinositol glycan anchor biosynthesis, class O.
    
 
 0.721
sptssb
Serine palmitoyltransferase, small subunit B.
      
 0.718
LOC113012162
Serine palmitoyltransferase, long chain base subunit 2a.
    
 
 0.694
sptlc2
Serine palmitoyltransferase, long chain base subunit 2b.
    
 
 0.694
ENSACLP00000036653
Isthmin 2b.
    
 
 0.694
sptlc3
Serine palmitoyltransferase, long chain base subunit 3.
    
 
 0.694
ism1
Isthmin 1.
    
 
 0.694
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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