Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
plekhf2Pleckstrin homology domain containing, family F (with FYVE domain) member 2. (245 aa)    
Predicted Functional Partners:
snx29
Sorting nexin 29.
    
 0.782
srek1ip1
CCHC-type domain-containing protein.
    
   0.770
nfyc
Nuclear transcription factor Y, gamma.
    
   0.764
plekhh2
Pleckstrin homology domain containing, family H (with MyTH4 domain) member 2.
      
 0.755
neurl1b
Neuralized E3 ubiquitin protein ligase 1B.
      
 0.720
fam43a
Family with sequence similarity 43 member A.
      
 0.719
PLEKHG1
Pleckstrin homology and RhoGEF domain containing G1.
     
 0.678
LOC113009920
TOX high mobility group box family member 4 a.
      
 0.666
nop53
Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family.
      
 0.610
LOC113027021
Leucine rich repeat containing 4C, genome duplicate a.
      
 0.600
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.