Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC113010065Uncharacterized protein. (239 aa)    
Predicted Functional Partners:
mta3
Metastasis associated 1 family, member 3.
   
 0.916
mta1
Metastasis associated 1.
   
 0.916
mta2
Metastasis associated 1 family, member 2.
   
 0.916
LOC113027513
Retinoblastoma binding protein 4, like.
   
 0.893
LOC113011815
Retinoblastoma binding protein 4.
   
 0.893
LOC113014472
WD_REPEATS_REGION domain-containing protein.
   
 0.893
LOC113026104
Methyl-CpG binding domain protein 2.
     
  0.871
LOC113016908
Methyl-CpG binding domain protein 3a.
     
  0.871
kdm1a
Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.
   
 0.843
ENSACLP00000004606
Chromodomain helicase DNA binding protein 5.
    
 0.839
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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