STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000004175BHLH domain-containing protein. (168 aa)    
Predicted Functional Partners:
ENSACLP00000032986
Twist family bHLH transcription factor 1a.
  
 
 
0.732
TCF4
Transcription factor 4.
    
 
 0.617
LOC113010171
Transcription factor 3a.
    
 
 0.617
tcf12
Transcription factor 12.
    
 
 0.617
LOC113016192
Transcription factor 3b.
    
 
 0.617
LOC113026641
BHLH domain-containing protein.
    
 
 0.616
LOC113018712
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
   
 
 0.582
ENSACLP00000017756
V-rel avian reticuloendotheliosis viral oncogene homolog A.
   
 
 0.538
rel
V-rel avian reticuloendotheliosis viral oncogene homolog.
   
 
 0.538
relb
V-rel avian reticuloendotheliosis viral oncogene homolog B.
   
 
 0.538
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.