Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MEX3DMex-3 RNA binding family member D. (535 aa)    
Predicted Functional Partners:
LOC113026104
Methyl-CpG binding domain protein 2.
     
 0.855
LOC113016908
Methyl-CpG binding domain protein 3a.
     
 0.855
nudcd1
NudC domain containing 1.
    
   0.766
mex3b
Mex-3 RNA binding family member B.
   
   0.753
ENSACLP00000016469
AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]
    
 
 0.752
ENSACLP00000040005
MYC binding protein 2.
    
 
 0.751
LOC113036202
14_3_3 domain-containing protein; Belongs to the 14-3-3 family.
    
   0.722
LOC113030401
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 2; Belongs to the 14-3-3 family.
    
   0.722
dhx9
DEAH (Asp-Glu-Ala-His) box helicase 9.
    
 
 0.665
LOC113030513
AP complex subunit beta.
    
   0.635
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
Server load: medium (46%) [HD]