Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC113027683-2Histone H3.3. (136 aa)    
Predicted Functional Partners:
LOC113030109
Lysine (K)-specific demethylase 6B, b.
   
 0.836
kdm6a
Lysine (K)-specific demethylase 6A.
   
 0.836
ENSACLP00000028690
Lysine (K)-specific demethylase 6B, a.
   
 0.836
LOC113015778
Lysine (K)-specific demethylase 6A, like.
   
 0.836
hat1
Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG.
    
 0.834
ENSACLP00000008692
AT rich interactive domain 4A (RBP1-like).
   
 0.804
ENSACLP00000034796
Translocase of outer mitochondrial membrane 20.
   
 0.804
ENSACLP00000026627
M-phase phosphoprotein 8.
    
 0.790
RPS27A
Ribosomal protein S27a.
   
 0.787
SETD2
SET domain containing 2, histone lysine methyltransferase.
    
 0.779
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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