Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ENSACLP00000004294Cytochrome P450, family 1, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (524 aa)    
Predicted Functional Partners:
comt
Catechol-O-methyltransferase b.
     
 0.935
gsto1
Glutathione S-transferase omega 2; Belongs to the GST superfamily.
    
 0.903
LOC113036927
Transmembrane O-methyltransferase.
     
 0.902
LOC113033188
Indoleamine 2,3-dioxygenase 1.
   
 
 0.902
ENSACLP00000025069
Uncharacterized protein.
   
 
 0.902
ENSACLP00000026705
Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family.
  
 0.902
hsd17b8
Hydroxysteroid (17-beta) dehydrogenase 8.
   
 
 0.902
ENSACLP00000037360
Epoxide hydrolase 5.
  
 0.902
LOC113011007
Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.
  
 
 0.893
ephx2
Epoxide hydrolase 2, cytoplasmic.
   
 0.891
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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