Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACLP00000004314GTP cyclohydrolase I feedback regulator. (177 aa)    
Predicted Functional Partners:
LOC113028261
GTP cyclohydrolase 2.
    
 0.985
gch1
GTP cyclohydrolase 1.
    
 0.985
pts
6-pyruvoyltetrahydropterin synthase.
     
 0.897
qdpr
Quinoid dihydropteridine reductase a.
   
  
 0.727
spr
Sepiapterin reductase b.
      
 0.727
exd1
3'-5' exonuclease domain-containing protein.
      
 0.725
dnajc12
DnaJ (Hsp40) homolog, subfamily C, member 12.
      
 0.674
dtymk
Deoxythymidylate kinase (thymidylate kinase).
      
 0.666
ENSACLP00000029920
MNAT1 component of CDK activating kinase.
      
 0.658
dhfr
Dihydrofolate reductase.
   
  
 0.623
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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