Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000004316Vacuole membrane protein 1. (400 aa)    
Predicted Functional Partners:
becn1
Beclin 1, autophagy related.
   
 0.949
atg13
Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily.
     
 0.935
tp53inp2
Uncharacterized protein.
     
 0.902
LOC113027707
Si:ch211-260e23.9.
     
  0.871
tp53inp1
Tumor protein p53 inducible nuclear protein 1.
     
 0.857
ENSACLP00000001139
Zgc:162297.
     
  0.765
tmem64
Transmembrane protein 64.
    
 
 0.725
auts2
Activator of transcription and developmental regulator AUTS2 a.
      
 0.672
gas6
Uncharacterized protein.
      
 0.638
LOC113035867
Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
      
 0.615
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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