Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC113033281Hexokinase 2. (920 aa)    
Predicted Functional Partners:
h6pd
Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase).
  
 
 0.937
gckr
Uncharacterized protein.
    
 0.932
taldo1
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
   
 0.911
LOC113025863
Glucose-6-phosphate isomerase; Belongs to the GPI family.
   
 0.908
LOC113024994
Glucose-6-phosphate isomerase; Belongs to the GPI family.
   
 0.908
gnpnat1
Glucosamine 6-phosphate N-acetyltransferase.
   
 0.907
g6pc3
Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family.
     
 0.907
LOC113022565
ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
   
 
 0.906
LOC113028116
Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family.
     
 0.906
G6PD
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.
   
 
 0.905
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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