Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000004394Uncharacterized protein. (275 aa)    
Predicted Functional Partners:
ENSACLP00000006058
Protein S100; Belongs to the S-100 family.
    
  0.677
LOC113015367
Protein S100; Belongs to the S-100 family.
   
 0.662
ENSACLP00000009309
AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]
    
  0.626
ENSACLP00000018109
Perilipin 6.
     
  0.555
LOC113015361
S100 calcium binding protein U; Belongs to the S-100 family.
     
 0.542
anxa1
Annexin.
   
  0.528
LOC113026782
Annexin.
   
  0.528
anxa2
Annexin.
   
  0.528
s100a14
S_100 domain-containing protein; Belongs to the S-100 family.
     
 0.520
ENSACLP00000008827
NSL1 component of MIS12 kinetochore complex.
    
  0.507
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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