Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
esf1ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae). (745 aa)    
Predicted Functional Partners:
ddx10
RNA helicase.
   
 
 0.995
nol10
Nucleolar protein 10.
   
 
 0.994
utp6
UTP6 small subunit processome component.
   
 
 0.991
mphosph10
U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing; Belongs to the MPP10 family.
   
 
 0.990
utp3
UTP3 small subunit processome component.
   
 
 0.989
utp18
WD_REPEATS_REGION domain-containing protein.
   
 
 0.989
aatf
Apoptosis antagonizing transcription factor.
   
 
 0.989
nom1
Nucleolar protein with MIF4G domain 1.
   
 
 0.988
nol6
Nucleolar protein 6.
   
 
 0.987
wdr36
WD repeat domain 36.
   
 
 0.987
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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