STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000004437Uncharacterized protein. (100 aa)    
Predicted Functional Partners:
guk1
Guanylate kinase 1a.
   
 
  0.844
ENSACLP00000030164
Guanylate kinase 1b.
   
 
  0.841
pde6g
Phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog b.
  
 
 
0.743
pde6d
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide [...]
     
 0.604
gnb5
Guanine nucleotide binding protein (G protein), beta 5a.
   
 
 0.528
ENSACLP00000020432
Guanine nucleotide binding protein (G protein), beta polypeptide 2.
   
 
 0.528
LOC113022298
Guanine nucleotide binding protein (G protein), beta polypeptide 1b.
   
 
 0.528
GNB5
Guanine nucleotide binding protein (G protein), beta 5b.
   
 
 0.528
LOC113015060
Guanine nucleotide binding protein (G protein), beta polypeptide 3b.
   
 
 0.528
LOC113013015
Guanine nucleotide binding protein (G protein), beta polypeptide 1a.
   
 
 0.528
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.