Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000004457Rho guanine nucleotide exchange factor (GEF) 10-like a. (1005 aa)    
Predicted Functional Partners:
sting1
Transmembrane protein 173.
   
 0.853
ENSACLP00000010589
Tumor protein p53 binding protein, 1.
    
  0.746
LOC113022989
Cell division cycle 42.
    
 0.551
uchl5
Ubiquitin carboxyl-terminal hydrolase.
      
 0.533
ENSACLP00000015926
Glyoxylate reductase 1 homolog (Arabidopsis).
    
   0.522
afmid
Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.
   
  
 0.522
LOC113029924
Uncharacterized protein.
     
  0.517
ENSACLP00000023566
Ras homolog family member H.
    
 0.512
rhoq
Ras homolog family member Q.
    
 0.512
arhgef11
Rho guanine nucleotide exchange factor (GEF) 11.
    
 0.511
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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