Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC113008783SMYD family member 5. (417 aa)    
Predicted Functional Partners:
ENSACLP00000029365
Lysine (K)-specific methyltransferase 2E.
    
 0.812
LOC113018712
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.795
SETD2
SET domain containing 2, histone lysine methyltransferase.
     
 0.781
dot1l
Histone-lysine N-methyltransferase, H3 lysine-79 specific.
    
 0.759
setd1b
SET domain containing 1B, histone lysine methyltransferase a.
    
 0.740
setd1a
SET domain containing 1A, histone lysine methyltransferase.
    
 0.740
LOC113022928
SET domain and mariner transposase fusion gene.
     
 0.727
eif2s3
Eukaryotic translation initiation factor 2, subunit 3 gamma.
   
  0.714
ENSACLP00000018302
Uncharacterized protein.
    
 0.709
ENSACLP00000008367
SET domain containing 7, histone lysine methyltransferase.
   
 
 0.696
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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