ENSACLP00000004606 protein (Astatotilapia calliptera)

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ENSACLP00000004606

Chromodomain helicase DNA binding protein 5. (1774 aa)

Predicted Functional Partners:

LOC113014899

0.936

HDAC2

0.936

HDAC1

0.936

mta3

0.928

mta1

0.928

mta2

0.928

gatad2b

0.926

LOC113011262

0.922

gatad2a

0.922

kdm1a

0.901

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSACLP00000004606	HDAC1	ENSACLP00000004606	ENSACLP00000028974	Chromodomain helicase DNA binding protein 5.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.936
ENSACLP00000004606	HDAC2	ENSACLP00000004606	ENSACLP00000028439	Chromodomain helicase DNA binding protein 5.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.936
ENSACLP00000004606	LOC113011262	ENSACLP00000004606	ENSACLP00000003021	Chromodomain helicase DNA binding protein 5.	GATA zinc finger domain containing 2A.	0.922
ENSACLP00000004606	LOC113014899	ENSACLP00000004606	ENSACLP00000020037	Chromodomain helicase DNA binding protein 5.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.936
ENSACLP00000004606	gatad2a	ENSACLP00000004606	ENSACLP00000006744	Chromodomain helicase DNA binding protein 5.	GATA zinc finger domain containing 2Ab.	0.922
ENSACLP00000004606	gatad2b	ENSACLP00000004606	ENSACLP00000024661	Chromodomain helicase DNA binding protein 5.	GATA zinc finger domain containing 2B.	0.926
ENSACLP00000004606	kdm1a	ENSACLP00000004606	ENSACLP00000022320	Chromodomain helicase DNA binding protein 5.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.901
ENSACLP00000004606	mta1	ENSACLP00000004606	ENSACLP00000011272	Chromodomain helicase DNA binding protein 5.	Metastasis associated 1.	0.928
ENSACLP00000004606	mta2	ENSACLP00000004606	ENSACLP00000022559	Chromodomain helicase DNA binding protein 5.	Metastasis associated 1 family, member 2.	0.928
ENSACLP00000004606	mta3	ENSACLP00000004606	ENSACLP00000002742	Chromodomain helicase DNA binding protein 5.	Metastasis associated 1 family, member 3.	0.928
HDAC1	ENSACLP00000004606	ENSACLP00000028974	ENSACLP00000004606	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Chromodomain helicase DNA binding protein 5.	0.936
HDAC1	HDAC2	ENSACLP00000028974	ENSACLP00000028439	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.938
HDAC1	LOC113011262	ENSACLP00000028974	ENSACLP00000003021	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	GATA zinc finger domain containing 2A.	0.885
HDAC1	LOC113014899	ENSACLP00000028974	ENSACLP00000020037	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.543
HDAC1	gatad2a	ENSACLP00000028974	ENSACLP00000006744	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	GATA zinc finger domain containing 2Ab.	0.885
HDAC1	gatad2b	ENSACLP00000028974	ENSACLP00000024661	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	GATA zinc finger domain containing 2B.	0.904
HDAC1	kdm1a	ENSACLP00000028974	ENSACLP00000022320	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.958
HDAC1	mta1	ENSACLP00000028974	ENSACLP00000011272	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Metastasis associated 1.	0.929
HDAC1	mta2	ENSACLP00000028974	ENSACLP00000022559	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Metastasis associated 1 family, member 2.	0.921
HDAC1	mta3	ENSACLP00000028974	ENSACLP00000002742	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Metastasis associated 1 family, member 3.	0.921